ColoZone Plus is a natural, drug-free blend that stimulates your intestines and colon to help you feel better inside and out. Whether you suffer from constipation, want to boost your magnesium or feel like your body could be running more regularly, we’ve got you covered. Colo zone Plus is a magnesium-based premium and natural colon cleansing and detoxification product. It may help with bowel regularity and constipation, reduce stomach acid and also acts as a magnesium supplement.