A Fast-Absorbing, Non-Greasy Hydration Solution for Skin and Hair. Hemi-Squalane is a non-polar hydrocarbon that is produced from the fermentation of sugar-based feedstock. Squalane and Hemi-Squalane are both excellent non-comedogenic emollients that can help to reduce the ongoing loss of hydration that weakens dermal elasticity and suppleness. However, due to its low molecular weight, Hemi-Squalane has greater spreadability and leaves a light and dry after-feel, making it very suitable for reducing hair frizz. Note: The 100% Plant-Derived Hemi-Squalane used in our product is USDA Certified Bio-Based.